Universität Basel Universität Zürich Swiss Institute of Bioinformatics ETH Zurich École Polytechnique Fédérale de Lausanne  Friedrich Miescher Institute for Biomedical Research

EPPIC Web front end

EPPIC (Evolutionary protein protein interface classifier, Duarte et al, 2012) is a method to computationally assess the nature (biological or crystal contact) of protein-protein interfaces in crystal structures. It does so by using three criteria, two sequence entropy-based evolutionary ones and a geometric one, which are then combined into a “bio” or “xtal” call for each interface in a crystal. The main use of EPPIC is to aid interpretation of biomacromolecular structures and to guide experiments to probe protein-protein interfaces.



Short facts

  • Developed at PSI - Paul Scherrer Institut, Capitani team; web frontend and integration by SyBIT / ETHZ.

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E-mail: sybit(at)sympa.systemsx.ch | Wiki: SyBIT Wiki
Copyright © 2012,SyBIT - SystemsX.ch Biology IT.

E-mail: sybit(at)sympa.systemsx.ch
Wiki: SyBIT Wiki
Copyright © 2012,SyBIT - SystemsX.ch Biology IT.